Tetrahydrocannabiphorol (THC-P) is the cannabinoid that enjoys the status of being the most intoxicating cannabinoid in cannabis, at least that we know of so far. But, the question is, why does this cannabinoid cause such distinctively powerful effects? The answer has to do with how the cannabinoid works with the body, which gives us a ton of insight offered through research that was done after this cannabinoid was discovered.
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How Do Cannabinoids Work?
To have an understanding of how tetrahydrocannabiphorol works, we need to understand the relationship that all cannabinoids share with the body’s endocannabinoid system (ECS). The ECS is a system found in all mammals, and its job is to use cannabinoids to regulate individual processes of the body, with the overarching goal of bringing us into homeostasis.
Throughout our bodies, we find cannabinoid receptors, with each one able to regulate a specific process of the body, whether it be our sleep cycle, our mood, our inflammation levels, our pain tolerance, or so on. Cannabinoid receptors are divided up into two categories: CB1 receptors, located in the nervous system, and CB2 receptors, located mainly in the nervous system, digestive system and immune systems. Some cannabinoids work more strongly with CB1 receptors, some work more strongly with CB2 receptors, and some work with both in a more balanced way.
When a cannabinoid absorbs into our body, it attaches itself to specific cannabinoid receptors, and this process enables the cannabinoid receptors to regulate specific processes that affect our body and mind. And, specific cannabinoid receptors in the brain use cannabinoids to produce a psychoactive effect, and how strongly a particular cannabinoid attaches to those receptors determines the strength of the high, which explains why some cannabinoids are far more intoxicating than others.
There are over 100 individual cannabinoids in the hemp plant, and each one plays its own role in interacting with the endocannabinoid system, which is why each cannabinoid ultimately feels and behaves differently. This is why getting high off of delta 8 can feel so different from getting high off of THC-P, for example.
Theoretically, every time we consume a cannabinoid in general, we’re bringing our bodies closer to homeostasis, although it’s safe to say that the majority of people who take psychoactive cannabinoids are more interested in its immediate intoxicating effects, which are undeniably enjoyable and can be extremely valuable to maintaining our mood, physical comfort levels and more on a daily basis.
How Does THC-P Work with the Endocannabinoid System?
Tetrahydrocannabiphorol was discovered back in 2019, and as you can imagine, there hasn’t been much time for researchers to analyze it between then and now. But, we’re grateful for the fact that the researchers who discovered THC-P also put effort into studying its chemical structure and potential effects, to give us a surprising amount of insight into how it works in the body.
What makes THC-P the most intoxicating cannabinoid is its relationship to CB1 receptors – the ones that get us high, as we said earlier. THC-P attaches to these CB1 receptors at about 31x the rate as delta 9 THC, and because of that, THC-P’s effects are much, much more potent than those of delta 9’s – about 10 times so. Not only are the psychoactive effects of THC-P stronger, but so are the other effects that the cannabinoid can offer.
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What Effects Can THC-P Offer?
To date, there’s actually only one meaningful study on the effects of THC-P. But, it does offer a detailed insight into what it can do for us. We know that THC-P is 10 times as intoxicating as delta 9 THC, give or take – something that we covered earlier. The high is also described as being incredibly euphoric, and even offering a powerful body high.
Again, because the cannabinoid acts on CB1 receptors 31x more strongly than delta 9 THC, its other properties related to the nervous system may be quite powerful as well.
Final THC-P Working Thoughts
Tetrahydrocannabiphorol gets its phenomenally powerful effects from its distinctive relationship to cannabinoid receptors belonging to the endocannabinoid system – CB1 receptors, to be more exact. Understanding this crucial relationship gives us a better idea of what we can get out of THC-P, and how to derive from it the benefits that we’re searching for. And, at Binoid, you can enjoy all sorts of amazing THC-P products.
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